A liquid chromatography flow cell including an integrated light source and an integrated detection chamber. The integrated light source includes a plurality of light emitting diodes (LEDs), wherein each LED emits light of a specific wavelength. The light emitted from the integrated light source is directed to pass through a sample in a flow chamber of the flow cell without any optical conditioning, and the light not absorbed by the sample flows out of the flow chamber directly into the integrated detection chamber, where an intensity of the unabsorbed light is measured by detectors coupled to the integrated chamber.