Disclosed are a display substrate, a display panel, a display device. The display substrate includes pixel units on a substrate in form of array, gate lines in one-to-one correspondence to each row of pixel units, data lines between any two adjacent columns of pixel units and on sides, far away from the substrate, of gate lines, each pixel unit includes a pixel electrode, a thin film transistor configured to control the pixel electrode; each data line includes curved data line parts between any two pixel units, whose row directions are adjacent to each other, in two columns of pixel units on two sides of data line; each data line part includes a first part covered by a pixel electrode of pixel unit on one side of the data line part, a second part covered by a pixel electrode of pixel unit on the other side of the data line part.