A signal processing system (SPS) and related method. The system comprises an input interface (IN) for receiving at least two data sets, comprising a first data set and second data set. The first data set is generated by an X-ray detector sub-system (XDS) at a first pixel size and the second data set generated at a second pixel size different from the first pixel size. An estimator (EST) is configured to compute, based on the two data sets, an estimate of a charge sharing impact.