Invention Grant
- Patent Title: Regulated expression of antigen and/or regulated attenuation to enhance vaccine immunogenicity and/or safety
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Application No.: US16990033Application Date: 2020-08-11
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Publication No.: US11180765B2Publication Date: 2021-11-23
- Inventor: Roy Curtiss, III , Shifeng Wang , Soo-Young Wanda , Wei Kong
- Applicant: The Arizona Board of Regents for and on Behalf of Arizona State University , The Washington University
- Applicant Address: US AZ Scottsdale; US MO St. Louis
- Assignee: The Arizona Board of Regents for and on Behalf of Arizona State University,The Washington University
- Current Assignee: The Arizona Board of Regents for and on Behalf of Arizona State University,The Washington University
- Current Assignee Address: US AZ Scottsdale; US MO St. Louis
- Agency: McCarter & English, LLP
- Agent Marcie B. Clarke
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12N15/74 ; A61K35/74 ; C12N1/36 ; A61K39/00 ; A61K35/00

Abstract:
The invention relates to compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens of interest.
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