Invention Grant
- Patent Title: Subcutaneous administration of ADAMTS13
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Application No.: US16567048Application Date: 2019-09-11
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Publication No.: US11185575B2Publication Date: 2021-11-30
- Inventor: Alexandra Nathalie Kopic , Werner Hollriegl , Barbara Plaimauer , Hanspeter Rottensteiner , Eva-Maria Muchitsch
- Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Applicant Address: JP Osaka
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee Address: JP Osaka
- Agency: Troutman Pepper Hamilton Sanders LLP
- Main IPC: A61K38/48
- IPC: A61K38/48 ; C12N9/64 ; A61K9/00 ; A61K9/19
Abstract:
This invention relates to methods of subcutaneous administration of ADAMTS13 formulations to a treat a disease or condition associated with ADAMTS13 and VWF dysfunction. Furthermore, evidence of the unexpectedly high bioavailability of ADAMTS13 formulations administered subcutaneously is provided herein.
Information query
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