Invention Grant
- Patent Title: Dual NAV1.2/5HT2a inhibitors for treating CNS disorders
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Application No.: US16322278Application Date: 2016-08-04
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Publication No.: US11186564B2Publication Date: 2021-11-30
- Inventor: Michele L. R. Heffernan , Larry Wendell Hardy , Scott P. Brown , Lee W. Herman
- Applicant: Sunovion Pharmaceuticals Inc.
- Applicant Address: US MA Marlborough
- Assignee: Sunovion Pharmaceuticals Inc.
- Current Assignee: Sunovion Pharmaceuticals Inc.
- Current Assignee Address: US MA Marlborough
- Agency: Heslin Rothenberg Farley & Mesiti, P.C.
- International Application: PCT/US2016/045559 WO 20160804
- International Announcement: WO2018/026371 WO 20180208
- Main IPC: C07D211/22
- IPC: C07D211/22 ; C07D401/08 ; C07D401/14 ; C07D401/06 ; C07D401/12 ; C07D405/06 ; C07D471/04 ; C07D487/10 ; C07D491/107 ; C07D311/22 ; C07D217/24 ; C07D223/08 ; C07D235/12 ; C07D237/14 ; C07D413/06 ; C07D241/04 ; C07D243/08 ; C07D471/08 ; C07D491/048 ; C07D267/10 ; C07D275/04 ; C07D211/58 ; C07D403/06 ; C07D405/12 ; A61P25/28 ; C07D417/04 ; A61P25/18 ; C07D513/04 ; C07D211/42 ; C07D295/104 ; C07D207/36 ; C07D213/81 ; C07D491/20 ; C07D249/12 ; C07D221/20 ; C07D295/088 ; C07D311/58 ; C07D207/12 ; C07D211/44 ; C07D265/30 ; C07D277/66 ; C07D295/027 ; C07D295/073 ; C07D295/096 ; C07D295/108 ; C07D307/83 ; C07D311/08 ; C07D413/08 ; C07D471/10

Abstract:
Compounds of formula I: are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disorders in a patient in need are also disclosed. Such disorders include depression, bipolar disorder, pain, schizophrenia, obsessive compulsive disorder, addiction, social disorder, attention deficit hyperactivity disorder, an anxiety disorder, autism, a cognitive impairment, or a neuropsychiatric symptom such as apathy, depression, anxiety, psychosis, aggression, agitation, impulse control disorders, and sleep disorders in neurological disorders such as Alzheimer's and Parkinson's diseases.
Public/Granted literature
- US20190194163A1 DUAL NAV1.2/5HT2a INHIBITORS FOR TREATING CNS DISORDERS Public/Granted day:2019-06-27
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