A driver loading method and a server, where when receiving a service request, the server determines a first global index and a first global virtual function (VF) identifier corresponding to a first function description of a designated function included in the service request, determines a virtual machine (VM) corresponding to the service request, associates the first global VF identifier with the VM, allocates a first local index on the VM to the designated function, creates a correspondence between the first local index and the first function description, and sends the correspondence to the VM. The VM loads, according to the correspondence, a driver of the designated function for a first VF corresponding to the first global VF identifier. According to the foregoing method, different drivers can be loaded for VFs that have different functions and that are virtualized by a Peripheral Component Interconnect Express (PCIe) device.