Aspects of the disclosure relate to real-time knowledge-based widget prioritization and display. A computing platform may detect, via a computing device, a voice-based interaction between an enterprise agent and a customer. Then, the computing platform may cause, via the computing device, the voice-based interaction to be captured as audio data. The computing platform may then transform the audio data to textual data. Subsequently, the computing platform may identify, in the textual data, a customer query. Then, the computing platform may retrieve, in real-time and based on the voice-based interaction and from a repository of widgets, a first widget, where the first widget includes information at least partially responsive to the customer query. Then, the computing platform may display, to the enterprise agent and via a graphical user interface in use by the enterprise agent, the first widget.