- 专利标题： SOMCL-9112 solid dispersion and preparation method thereof and SOMCL-9112 solid preparation containing SOMCL-9112 solid dispersion
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申请号： US15574557申请日： 2016-05-13
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公开(公告)号： US11191761B2公开(公告)日： 2021-12-07
- 发明人: Shiyan Guo , Yong Gan , Ao Zhang , Zehong Miao , Li Gao , Jian Ding
- 申请人： SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES , Shanghai Acebright Pharmaceuticals Co., Ltd.
- 申请人地址： CN Shanghai; CN Pudong New District Shanghai
- 专利权人： SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES,Shanghai Acebright Pharmaceuticals Co., Ltd.
- 当前专利权人： SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES,Shanghai Acebright Pharmaceuticals Co., Ltd.
- 当前专利权人地址： CN Shanghai; CN Pudong New District Shanghai
- 代理机构： Panitch Schwarze Belisario & Nadel LLP
- 代理商 Lars H. Genieser
- 优先权： CN201510253480.7 20150518
- 国际申请： PCT/CN2016/082044 WO 20160513
- 国际公布： WO2016/184367 WO 20161124
- 主分类号： A61K31/502
- IPC分类号： A61K31/502 ; A61K47/40 ; A61K47/38 ; A61K47/34 ; A61K47/32 ; A61K9/48 ; A61K9/28 ; A61P35/00 ; A61K47/10 ; A61K9/10 ; A61K9/20 ; A61K9/08 ; A61K9/14
摘要：
Disclosed is an SOMCL-9112 solid dispersion. The SOMCL-9112 solid dispersion is characterized by being prepared from the following raw materials in percentage by weight: 5 percent to 60 percent of SOMCL-9112, 5 percent to 90 percent of pharmaceutically acceptable matrix polymer, 0 percent to 20 percent of surfactant, 0 percent to 20 percent of flow aid and 0 percent to 20 percent of plasticizer. Also disclosed are a preparation method of the SOMCL-9112 solid dispersion, a solid medicinal preparation containing the solid dispersion and application of the solid dispersion for preparing a medicine for treating cancer.