Invention Grant
- Patent Title: SOMCL-9112 solid dispersion and preparation method thereof and SOMCL-9112 solid preparation containing SOMCL-9112 solid dispersion
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Application No.: US15574557Application Date: 2016-05-13
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Publication No.: US11191761B2Publication Date: 2021-12-07
- Inventor: Shiyan Guo , Yong Gan , Ao Zhang , Zehong Miao , Li Gao , Jian Ding
- Applicant: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES , Shanghai Acebright Pharmaceuticals Co., Ltd.
- Applicant Address: CN Shanghai; CN Pudong New District Shanghai
- Assignee: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES,Shanghai Acebright Pharmaceuticals Co., Ltd.
- Current Assignee: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES,Shanghai Acebright Pharmaceuticals Co., Ltd.
- Current Assignee Address: CN Shanghai; CN Pudong New District Shanghai
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Agent Lars H. Genieser
- Priority: CN201510253480.7 20150518
- International Application: PCT/CN2016/082044 WO 20160513
- International Announcement: WO2016/184367 WO 20161124
- Main IPC: A61K31/502
- IPC: A61K31/502 ; A61K47/40 ; A61K47/38 ; A61K47/34 ; A61K47/32 ; A61K9/48 ; A61K9/28 ; A61P35/00 ; A61K47/10 ; A61K9/10 ; A61K9/20 ; A61K9/08 ; A61K9/14

Abstract:
Disclosed is an SOMCL-9112 solid dispersion. The SOMCL-9112 solid dispersion is characterized by being prepared from the following raw materials in percentage by weight: 5 percent to 60 percent of SOMCL-9112, 5 percent to 90 percent of pharmaceutically acceptable matrix polymer, 0 percent to 20 percent of surfactant, 0 percent to 20 percent of flow aid and 0 percent to 20 percent of plasticizer. Also disclosed are a preparation method of the SOMCL-9112 solid dispersion, a solid medicinal preparation containing the solid dispersion and application of the solid dispersion for preparing a medicine for treating cancer.
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