A method of manufacturing a seamless stainless steel pipe for Oil Country Tubular Goods by heating a billet having a specified chemical composition including forming the billet into a seamless steel pipe by applying hot working to the billet, cooling the seamless steel pipe to a room temperature at a cooling rate of air cooling or more, thereafter, performing quenching by heating the seamless steel pipe to a temperature of 850° C. or above, subsequently, cooling the seamless steel pipe to a temperature of 100° C. or below at a cooling rate of air cooling or more, and subsequently, applying tempering to the seamless steel pipe at a temperature of 700° C. or below for a specific holding time.