The present disclosure provides a display panel, a method of driving the display panel and a display device. Each signal input sub-circuitry of the display panel includes at least two transistors. A same control signal is applied to control signal lines corresponding to a same signal input sub-circuitry, different control signals are applied to control signal lines corresponding to different signal input sub-circuitries, and time periods within which the different control signals are at active levels are staggered from each other. A sum of width-to-length ratios of channels of the at least two transistors is equal to a first predetermined value, and an overlapping area of the gate electrode of each of the at least two transistors relative to an active layer of the transistor is smaller than a second predetermined value in a direction perpendicular to a base substrate of the display panel.