Invention Grant
- Patent Title: Crystal forms of amino lipids
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Application No.: US16493789Application Date: 2018-03-15
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Publication No.: US11203569B2Publication Date: 2021-12-21
- Inventor: Orn Almarsson , Eugene Cheung
- Applicant: ModernaTX, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ModernaTX, Inc.
- Current Assignee: ModernaTX, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Cooley LLP
- Agent Heidi A. Erlacher; Christine C. Pemberton
- International Application: PCT/US2018/022740 WO 20180315
- International Announcement: WO2018/170322 WO 20180920
- Main IPC: C07C229/24
- IPC: C07C229/24 ; C07C55/07 ; C07C65/03 ; C07C227/16 ; C07C229/12
Abstract:
Provided herein are novel solid forms of each of four compounds: (1) heptadecan-9-yl 8-((2-hydroxyethyl)amino)octanoate (“Compound 1”), (2) heptadecan-9-yl 8-((2-hydroxyethyl)(6-oxo-6-(undecyloxy)hexyl)amino)octanoate (“Compound 2”), (3) heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)-8-oxooctyl)amino)octanoate (“Compound 3”), and (6Z,9Z,28Z,31Z)-heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate (“MC3”), and related compositions and methods.
Information query
