Invention Grant
- Patent Title: Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR)
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Application No.: US15776591Application Date: 2016-11-17
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Publication No.: US11213586B2Publication Date: 2022-01-04
- Inventor: Changyu Wang , Nils Lonberg , Alan J. Korman , Mark J. Selby , Mohan Srinivasan , Karla A. Henning , Michelle Minhua Han , Guodong Chen , Richard Y. Huang , Indrani Chakraborty , Haichun Huang , Susan Chien-Szu Wong , Huiming Li , Bryan C. Barnhart , Aaron P. Yamniuk , Ming Lei , Liang Schweizer , Sandra V. Hatcher , Arvind Rajpal
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- International Application: PCT/US2016/062540 WO 20161117
- International Announcement: WO2017/087678 WO 20170526
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; G01N33/574 ; G01N33/68 ; A61K39/00
Abstract:
Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
Public/Granted literature
- US20180339042A1 ANTIBODIES AGAINST GLUCOCORTICOID-INDUCED TUMOR NECROSIS FACTOR RECEPTOR (GITR) AND USES THEREOF Public/Granted day:2018-11-29
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