Systems and methods are disclosed for denoising chrominance channels of images. For example, methods may include receiving an image from one or more image sensors; determining a set of weights for the image based on a luminance channel of the image, wherein a weight in the set of weights corresponds to a subject pixel and a candidate pixel and is determined based on luminance values of one or more pixels of the image centered at the subject pixel and one or more pixels of the image centered at the candidate pixel; applying the set of weights to chrominance channels of the image to obtain a denoised image, wherein the subject pixel of the denoised image is determined based on the weight multiplied by the candidate pixel of the image; and storing, displaying, or transmitting an output image based on the denoised image.