Invention Grant
- Patent Title: Combinations of FGFR4 inhibitors and bile acid sequestrants
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Application No.: US16347194Application Date: 2017-11-01
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Publication No.: US11229643B2Publication Date: 2022-01-25
- Inventor: Robin Alec Fairhurst , Diana Graus Porta , Jacqueline Kinyamu-Akunda , Andreas Joerg Mahl , Luigi Manenti , Andreas Weiss , Armin Wolf , Kuno Wuersch
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agency: Rimôn, P.C.
- International Application: PCT/IB2017/056787 WO 20171101
- International Announcement: WO2018/083603 WO 20180511
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/14

Abstract:
The present invention relates to a pharmaceutical combination comprising an FGFR4 inhibitor and a bile acid sequestrant, to the use of the pharmaceutical combination in the treatment of cancer, to the use of a bile acid sequestrant to reduce or mitigate side-effects associated with FGFR4 inhibition therapy.
Public/Granted literature
- US20200261444A1 COMBINATIONS OF FGFR4 INHIBITORS AND BILE ACID SEQUESTRANTS Public/Granted day:2020-08-20
Information query
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