- 专利标题： EBNA1 inhibitor crystalline forms, and methods of preparing and using same
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申请号： US16414198申请日： 2019-05-16
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公开(公告)号： US11242338B2公开(公告)日： 2022-02-08
- 发明人: Troy E. Messick , Paul M. Lieberman , Garry R. Smith , Arlindo L. Castelhano
- 申请人： THE WISTAR INSTITUTE
- 申请人地址： US PA Philadelphia
- 专利权人： THE WISTAR INSTITUTE
- 当前专利权人： THE WISTAR INSTITUTE
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Saul Ewing Arnstein & Lehr LLP
- 代理商 Kathryn Doyle; Domingos Silva
- 主分类号： A61K45/06
- IPC分类号： A61K45/06 ; A61K31/404 ; A61P31/22 ; A61P35/02 ; A61P25/28 ; C07D405/12 ; A61K9/00
摘要：
The invention relates, in certain aspects, to developable forms of certain compounds that are useful to treat and/or prevent EBV infection and related conditions in a subject. The invention further provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection and/or lytic EBV infection.
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