- 专利标题： Monoclonal antibodies and cocktails for treatment of Ebola infections
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申请号： US16896991申请日： 2020-06-09
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公开(公告)号： US11242379B2公开(公告)日： 2022-02-08
- 发明人: Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
- 申请人： MAPP BIOPHARMACEUTICAL, INC. , Albert Einstein College of Medicine , Adimab, LLC
- 申请人地址： US CA San Diego; US NY Bronx; US NH Lebanon
- 专利权人： MAPP BIOPHARMACEUTICAL, INC.,Albert Einstein College of Medicine,Adimab, LLC
- 当前专利权人： MAPP BIOPHARMACEUTICAL, INC.,Albert Einstein College of Medicine,Adimab, LLC
- 当前专利权人地址： US CA San Diego; US NY Bronx; US NH Lebanon
- 代理机构： Optima Law Group, APC
- 代理商 Thomas E. Jurgensen
- 主分类号： C07K16/10
- IPC分类号： C07K16/10 ; A61P31/14 ; A61K39/42 ; A61K39/00
摘要：
Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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