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公开(公告)号：US20180244758A1
公开(公告)日：2018-08-30
申请号：US15898524
申请日：2018-02-17
发明人： Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
CPC分类号： C07K16/10 , A61K39/42 , A61K2039/505 , A61K2039/545 , A61K2039/55 , A61K2039/57 , A61K2039/6075 , A61K2039/62 , A61P31/14 , C07K2317/76
摘要： Described herein are compositions and methods for the prevention and treatment of ebolavirus infection certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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公开(公告)号：US11242378B2
公开(公告)日：2022-02-08
申请号：US16896980
申请日：2020-06-09
发明人： Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
摘要： Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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公开(公告)号：US20200299363A1
公开(公告)日：2020-09-24
申请号：US16897027
申请日：2020-06-09
发明人： Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
摘要： Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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公开(公告)号：US11242379B2
公开(公告)日：2022-02-08
申请号：US16896991
申请日：2020-06-09
发明人： Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
摘要： Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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公开(公告)号：US20230044044A1
公开(公告)日：2023-02-09
申请号：US17856774
申请日：2022-07-01
发明人： Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
摘要： Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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公开(公告)号：US11407816B2
公开(公告)日：2022-08-09
申请号：US16897013
申请日：2020-06-09
发明人： Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
摘要： Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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公开(公告)号：US11254732B2
公开(公告)日：2022-02-22
申请号：US16897001
申请日：2020-06-09
发明人： Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
摘要： Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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公开(公告)号：US20200299361A1
公开(公告)日：2020-09-24
申请号：US16897001
申请日：2020-06-09
发明人： Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
摘要： Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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公开(公告)号：US20200299362A1
公开(公告)日：2020-09-24
申请号：US16897013
申请日：2020-06-09
发明人： Zachary A. Bornholdt , Larry Zeitlin , Kartik Chandran , Anna Wec , Laura Walker
摘要： Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
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