Invention Grant
- Patent Title: Method for obtaining a small RNA-enriched aqueous extract of Anethum graveolens
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Application No.: US16612365Application Date: 2018-04-27
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Publication No.: US11248224B2Publication Date: 2022-02-15
- Inventor: Elodie Oger , Jean-Marie Botto
- Applicant: ISP Investments LLC
- Applicant Address: US DE Wilmington
- Assignee: ISP Investments LLC
- Current Assignee: ISP Investments LLC
- Current Assignee Address: US DE Wilmington
- Agent William J. Davis; Nathalie Tietcheu
- Priority: FR1770486 20170512
- International Application: PCT/EP2018/060926 WO 20180427
- International Announcement: WO2018/206322 WO 20181115
- Main IPC: C12N5/10
- IPC: C12N5/10 ; A61K8/9789 ; C12N15/10 ; A61Q19/08 ; A61Q5/00 ; A61Q19/00

Abstract:
The invention relates to a method for obtaining an aqueous extract of Anethum graveolens, enriched with small RNAs having a maximum length of 150 nucleotides, from a plant material, said method comprising the following steps: a) aerial parts of dill is brought into contact with water; b) tetrasodium ethylenediaminetetraacetic acid (EDTA) is added at a pH of between 10.5 and 11; c) the pH of the mixture obtained in b) is then adjusted to a value of between 6 and 8; d) the mixture obtained in c) is purified; and e) the pH is checked and readjusted if necessary to a value of between 6 and 8. The invention also relates to an aqueous extract of Anethum graveolens, enriched with small RNAs having a maximum length of 150 nucleotides, obtained by the method.
Public/Granted literature
- US20210155921A1 METHOD FOR OBTAINING A SMALL RNA-ENRICHED AQUEOUS EXTRACT OF ANETHUM GRAVEOLENS Public/Granted day:2021-05-27
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