- Patent Title: [3.3.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors
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Application No.: US17057959Application Date: 2019-05-28
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Publication No.: US11267786B2Publication Date: 2022-03-08
- Inventor: Shuwen He , Yongxin Han , Alexander Pasternak
- Applicant: Merck Sharp & Dohme Corp. , Shuwen He , Yongxin Han , Alexander Pasternak
- Applicant Address: US NJ Rahway; US NJ Fanwood; US MA Needham; US MA Jamaica Plain
- Assignee: Merck Sharp & Dohme Corp.,Shuwen He,Yongxin Han,Alexander Pasternak
- Current Assignee: Merck Sharp & Dohme Corp.,Shuwen He,Yongxin Han,Alexander Pasternak
- Current Assignee Address: US NJ Rahway; US NJ Fanwood; US MA Needham; US MA Jamaica Plain
- Agent Yong Zhao; Catherine D. Fitch
- International Application: PCT/US2019/034089 WO 20190528
- International Announcement: WO2019/231871 WO 20191205
- Main IPC: C07D215/14
- IPC: C07D215/14 ; A61K45/06
![[3.3.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors](/abs-image/US/2022/03/08/US11267786B2/abs.jpg.150x150.jpg)
Abstract:
Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
Public/Granted literature
- US20210214308A1 NOVEL [3.3.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS Public/Granted day:2021-07-15
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