- 专利标题： ICAM-1 aptamers, diagnostic and therapeutic uses thereof
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申请号： US17262835申请日： 2019-07-24
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公开(公告)号： US11274308B2公开(公告)日： 2022-03-15
- 发明人: Vittorio De Franciscis , Silvia Catuogno , Carla Lucia Esposito , Alessandro Maiocchi , Margherita Iaboni , Luisa Poggi , Erika Reitano
- 申请人： BRACCO IMAGING S.P.A.
- 申请人地址： IT Milan
- 专利权人： BRACCO IMAGING S.P.A.
- 当前专利权人： BRACCO IMAGING S.P.A.
- 当前专利权人地址： IT Milan
- 代理机构： Vivicar Law, PLLC
- 优先权： EP18185794 20180726
- 国际申请： PCT/EP2019/069917 WO 20190724
- 国际公布： WO2020/020947 WO 20200130
- 主分类号： C12N15/115
- IPC分类号： C12N15/115 ; C12Q1/68
摘要：
The present invention provides nucleic acid aptamers binding to the Intercellular Adhesion Molecule-1 (ICAM-1), derivatives and conjugates thereof and their use as diagnostic tools, particularly for the imaging of organs and tissues expressing ICAM-1, or as therapeutic agents for prevention or treatment of ICAM-1-related diseases.
公开/授权文献
- US20210292762A1 ICAM-1 APTAMERS, DIAGNOSTIC AND THERAPEUTIC USES THEREOF 公开/授权日：2021-09-23
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