Arrangements disclosed in the present disclosure provide an array substrate, a manufacturing, a display panel and a display device. The array substrate comprises: a first signal line comprising a first extension portion along a first direction and a first connection portion along a second direction, which is provided with via holes; a second signal line comprising a second extension portion and a second connection portion along the second direction, which is provided with via holes; and a conductive connection layer, configured to connect the first signal line and the second signal line through the via holes of the first connection portion and second connection portion. The first connection portion and the second connection portion are lined up in a direction perpendicular to the second direction.