发明授权
- 专利标题： Methods and compositions for reducing side effects in chemotherapeutic treatments
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申请号： US16630989申请日： 2018-07-13
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公开(公告)号： US11278548B2公开(公告)日： 2022-03-22
- 发明人: Mario Lacouture , Philippe Andres
- 申请人： Galderma Research and Development
- 申请人地址： CH Lausanne
- 专利权人： Galderma Research and Development
- 当前专利权人： Galderma Research and Development
- 当前专利权人地址： CH Lausanne
- 代理机构： Ice Miller LLP
- 国际申请： PCT/US2018/041952 WO 20180713
- 国际公布： WO2019/014518 WO 20190117
- 主分类号： A61K31/498
- IPC分类号： A61K31/498 ; A61P17/00 ; A61K31/137 ; A61K31/4174 ; A61K31/7048 ; A61K45/06
摘要：
A method of preventing or reducing dermatological side effects of the therapeutic agents in a subject without substantial loss in efficacy, where the therapeutic agents would otherwise have significant effects, is described. In particular, the beneficial effects are achieved by using an alpha-2 adrenergic agonist to isolate body areas from pharmacological effects of the therapeutic agents, such as a chemotherapeutic agent, and to prevent or reduce inflammatory processes.