-
公开(公告)号:US11278548B2
公开(公告)日:2022-03-22
申请号:US16630989
申请日:2018-07-13
发明人: Mario Lacouture , Philippe Andres
IPC分类号: A61K31/498 , A61P17/00 , A61K31/137 , A61K31/4174 , A61K31/7048 , A61K45/06
摘要: A method of preventing or reducing dermatological side effects of the therapeutic agents in a subject without substantial loss in efficacy, where the therapeutic agents would otherwise have significant effects, is described. In particular, the beneficial effects are achieved by using an alpha-2 adrenergic agonist to isolate body areas from pharmacological effects of the therapeutic agents, such as a chemotherapeutic agent, and to prevent or reduce inflammatory processes.