Invention Grant
- Patent Title: Automated instrumentation for production of T-cell receptor peptide libraries
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Application No.: US17016454Application Date: 2020-09-10
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Publication No.: US11293117B2Publication Date: 2022-04-05
- Inventor: Stephen Federowicz , Deanna Church , Michael Graige
- Applicant: Inscripta, Inc.
- Applicant Address: US CO Boulder
- Assignee: Inscripta, Inc.
- Current Assignee: Inscripta, Inc.
- Current Assignee Address: US CO Boulder
- Agent Sarah Brashears
- Main IPC: C07K14/74
- IPC: C07K14/74 ; C40B50/06 ; C12N9/22 ; C40B30/04 ; C40B40/10 ; C07K16/28 ; C12N15/10 ; C12N15/81 ; C12N15/85 ; C12N15/90 ; C40B20/04 ; C40B40/02 ; C40B70/00

Abstract:
The present disclosure provides instrumentation and automated methods for creating cell surface display libraries, where the cells of the library display engineered peptides on their cell surfaces for identification of antigens that bind to T-cell receptors. The engineered peptides may be putative antigens or binding regions of the T-cell receptors.
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