Invention Grant
- Patent Title: Lipid prodrugs of mycophenolic acid and uses thereof
-
Application No.: US16955162Application Date: 2018-12-19
-
Publication No.: US11304954B2Publication Date: 2022-04-19
- Inventor: Daniel Kenneth Bonner , Ketki Karanam , Sifei Han , Luojuan Hu , Christopher John Hamilton Porter , Tim Quach , Rishab R. Shyam , Jamie Simpson , Natalie Trevaskis
- Applicant: PureTech LYT, Inc. , Monash University
- Applicant Address: US MA Boston; AU Clayton
- Assignee: PureTech LYT, Inc.,Monash University
- Current Assignee: PureTech LYT, Inc.,Monash University
- Current Assignee Address: US MA Boston; AU Clayton
- Agency: Womble Bond Dickinson (US) LLP
- Agent Danielle L. Herritt; Mark R. Deluca
- International Application: PCT/US2018/066585 WO 20181219
- International Announcement: WO2019/126378 WO 20190627
- Main IPC: C07D413/12
- IPC: C07D413/12 ; A61K31/5377 ; A61K47/54 ; A61P37/06
Abstract:
The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.
Public/Granted literature
- US3168109A Domestic water mixing and diverting valve assembly Public/Granted day:1965-02-02
Information query
