Invention Grant
- Patent Title: Process for producing fluorinated compounds using alcohol solvent having unsaturated hydrocarbon
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Application No.: US16888272Application Date: 2020-05-29
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Publication No.: US11306091B2Publication Date: 2022-04-19
- Inventor: Dae Yoon Chi , Byoung Se Lee , So Young Chu , Hyeon Jin Jeong , Hyeon Seok Kim
- Applicant: FUTURECHEM CO., LTD
- Applicant Address: KR Seoul
- Assignee: FUTURECHEM CO., LTD
- Current Assignee: FUTURECHEM CO., LTD
- Current Assignee Address: KR Seoul
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: KR10-2019-0075528 20190625
- Main IPC: C07D471/08
- IPC: C07D471/08 ; C07D417/04 ; C07C209/74 ; C07C43/225 ; C07H1/00
Abstract:
The present invention relates to a process for producing an organofluoro compound including [18F]fluorine, and by using a solvent represented by Formula 1 in nucleophilic fluorination reaction, an organofluoro compound may be prepared at a high yield. In addition, since the solvent has very excellent solubility for a precursor compound, the solvent is suitable for the automated synthesis of 18F-labeled radiopharmaceuticals.
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