In accordance with implementations of the subject matter described herein, there provides a solution for multi-path RDMA transmission. In the solution, at least one packet is generated based on an RDMA message to be transmitted from a first device to a second device. The first device has an RDMA connection with the second device via a plurality of paths. A first packet in the at least one packet includes a plurality of fields, which include information for transmitting the first packet over a first path of the plurality of paths. The at least one packet is transmitted to the second device over the plurality of paths via an RDMA protocol. The first packet is transmitted over the first path. The multi-path RDMA transmission solution according to the subject matter described herein can efficiently utilize rich network paths while maintaining a low memory footprint in a network interface card.