Methods and apparatuses for handling device-to-device feedback transmission in a wireless communication system are disclosed herein. In one method, a first device receives a configuration for operating in a network scheduling mode for acquiring sidelink resources. The first device receives a sidelink control information with a report request from a second device. The first device triggers or is triggered to transmit a report to the second device in response to the report request. If the first device has no available sidelink resource for transmitting the report, the first device triggers a scheduling request. The first device transmits a signaling of the scheduling request to the network. The first device receives a sidelink grant from the network. The first device utilizes sidelink resource(s) indicated by the sidelink grant to transmit the report to the second device.