Invention Grant
- Patent Title: NSD family inhibitors and methods of treatment therewith
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Application No.: US16213564Application Date: 2018-12-07
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Publication No.: US11324729B2Publication Date: 2022-05-10
- Inventor: Tomasz Cierpicki , Jolanta Grembecka , Huang Huang , Sergei Zari , Hyo Je Cho , Mykhaylo Potopnyk , Sergii Dudkin , Wenbing Chen , Yassir Adam , Christina Howard , EunGi Kim
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones SC
- Agent David W. Staple
- Main IPC: A61K31/428
- IPC: A61K31/428 ; A61P35/00
Abstract:
Provided herein are small molecule inhibitors of NSD1, NSD2 and/or NSD3 activity, and methods of use thereof for the treatment of disease, including leukemia, breast cancer, osteosarcoma, lung and prostate cancers and other solid tumors as well as other diseases dependent on the activity of NSD1, NSD2 and/or NSD3.
Public/Granted literature
- US20190183865A1 NSD FAMILY INHIBITORS AND METHODS OF TREATMENT THEREWITH Public/Granted day:2019-06-20
Information query
IPC分类:
