专利检索 ap:("The Regents of the University of Michigan") AND inv:"Wenbing Chen" 第 1 页

1.

发明申请
NSD FAMILY INHIBITORS AND METHODS OF TREATMENT THEREWITH 审中-公开

公开(公告)号：US20190183865A1

公开(公告)日：2019-06-20

申请号：US16213564

申请日：2018-12-07

申请人： The Regents of the University of Michigan

发明人： Tomasz Cierpicki , Jolanta Grembecka , Huang Huang , Sergi Zari , Hyo Je Cho , Mykhaylo Potopnyk , Sergeii Dudkin , Wenbing Chen , Yassir Adam , Christina Howard , EunGi Kim

IPC分类号： A61K31/428 , A61P35/00

CPC分类号： A61K31/428 , A61P35/00

摘要： Provided herein are small molecule inhibitors of NSD1, NSD2 and/or NSD3 activity, and methods of use thereof for the treatment of disease, including leukemia, breast cancer, osteosarcoma, lung and prostate cancers and other solid tumors as well as other diseases dependent on the activity of NSD1, NSD2 and/or NSD3.

2.

发明授权
NSD family inhibitors and methods of treatment therewith 有权

公开(公告)号：US11324729B2

公开(公告)日：2022-05-10

申请号：US16213564

申请日：2018-12-07

申请人： The Regents of the University of Michigan

发明人： Tomasz Cierpicki , Jolanta Grembecka , Huang Huang , Sergei Zari , Hyo Je Cho , Mykhaylo Potopnyk , Sergii Dudkin , Wenbing Chen , Yassir Adam , Christina Howard , EunGi Kim

IPC分类号： A61K31/428 , A61P35/00

摘要： Provided herein are small molecule inhibitors of NSD1, NSD2 and/or NSD3 activity, and methods of use thereof for the treatment of disease, including leukemia, breast cancer, osteosarcoma, lung and prostate cancers and other solid tumors as well as other diseases dependent on the activity of NSD1, NSD2 and/or NSD3.

3.

发明申请
NSD FAMILY INHIBITORS AND METHODS OF TREATMENT THEREWITH 有权

公开(公告)号：US20230046569A1

公开(公告)日：2023-02-16

申请号：US17729836

申请日：2022-04-26

申请人： The Regents of the University of Michigan

发明人： Tomasz Cierpicki , Jolanta Grembecka , Huang Huang , Sergei Zari , Hyo Je Cho , Mykhaylo Potopnyk , Sergii Dudkin , Wenbing Chen , Yassir Adam , Christina Howard , EunGi Kim

IPC分类号： A61K31/428 , A61P35/00

摘要： Provided herein are small molecule inhibitors of NSD1, NSD2 and/or NSD3 activity, and methods of use thereof for the treatment of disease, including leukemia, breast cancer, osteosarcoma, lung and prostate cancers and other solid tumors as well as other diseases dependent on the activity of NSD1, NSD2 and/or NSD3.