Embodiments for optimizing dynamic resource allocations for storage-dependent workloads in a disaggregated computing environment. A new workload is assigned to a subset of a plurality of processors, the subset of processors assigned a subset of a plurality of memory devices associated with a plurality of storage devices. A determination is made that the new workload is categorized as a storage-dependent workload having a storage need which can be met primarily by a subset of the storage devices after having identified whether data requests associated with the new workload can be satisfied by the subset of memory devices. Pursuant to determining the new workload is the storage-dependent workload, a storage related action is proactively performed to increase efficiency of the new workload prior to commencement of a performance of the new workload.