Invention Grant
- Patent Title: Combination therapy for treating disorders of the ear
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Application No.: US16483654Application Date: 2018-01-31
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Publication No.: US11331373B2Publication Date: 2022-05-17
- Inventor: Jian Zuo , Fei Zheng , Tetsuji Yamashita , Wanda Layman
- Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
- Applicant Address: US TN Memphis
- Assignee: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
- Current Assignee: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
- Current Assignee Address: US TN Memphis
- Agency: Veritay Group IP, PLLC
- Agent Susan Fentress; Liam O'Donnell
- International Application: PCT/US2018/016085 WO 20180131
- International Announcement: WO2018/148071 WO 20180816
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K38/17 ; A01K67/027 ; A61K9/00 ; A61K31/7105 ; A61K45/06
Abstract:
Methods and compositions using a nucleic acid molecule encoding an atonal-associated factor in combination with a co-transcription factor and/or inhibitor of a gene silencing complex to change the sensory perception of an animal are described.
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