The embodiments of the present disclosure relate to a microfluidic chip. The microfluidic chip may include a substrate. The substrate may include an electrode layer on a base substrate, a dielectric layer on the electrode layer, and a lyophobic layer on the dielectric layer. The electrode layer may include a plurality of electrode units. Each of the plurality of electrode units may be configured to realize both droplet detection and droplet driving in response to a detection signal and a driving signal respectively.