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公开(公告)号：US11351547B2
公开(公告)日：2022-06-07
申请号：US16610318
申请日：2019-03-26
发明人： Yue Geng , Peizhi Cai , Fengchun Pang , Le Gu , Chuncheng Che , Nan Zhao
IPC分类号： B01L3/00
摘要： Micro-fluidic chip comprises substrate and plurality of driving circuits on substrate, each of plurality of driving circuits comprising: driving electrode comprising first electrode plate and second electrode plate made of different materials on substrate, first electrode plate being electrically coupled to second electrode plate; and detecting sub-circuit comprising first signal terminal electrically coupled to first electrode plate and second signal terminal electrically coupled to second electrode plate, wherein micro-fluidic chip further comprises: voltage supply sub-circuit configured to supply driving voltage to first signal terminal to control droplet to move toward driving circuit during droplet driving stage, and configured to supply constant voltage to first signal terminal, during temperature detecting stage, and wherein detecting sub-circuit is configured to measure voltage difference between first signal terminal and second signal terminal, and obtain temperature of droplet on second electrode plate according to voltage difference, during temperature detecting stage.
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公开(公告)号：US20210331162A1
公开(公告)日：2021-10-28
申请号：US16626490
申请日：2019-07-26
发明人： Nan Zhao , Peizhi Cai , Haochen Cui , Yuelei Xiao , Fengchun Pang , Le Gu , Yingying Zhao , Hui Liao , Yue Geng , Wenliang Yao
摘要： A microfluidic apparatus is provided. The microfluidic apparatus includes an electrochromic layer including a plurality of individually independently addressable regions; a microfluidic layer defining a microfluidic channel for allowing a microfluid to pass therethrough; and a plurality of photodetectors configured to detect light transmit through the microfluid. The electrochromic layer is configured to be switched between a first state in which the plurality of individually independently addressable regions of the electrochromic layer are substantially transmissive, and a second state in which at least a first one of the plurality of individually independently addressable regions of the electrochromic layer in a region corresponding to a position of the microfluid is substantially transmissive, at least a second one of the plurality of individually independently addressable regions of the electrochromic layer outside the region corresponding to the position of the microfluid is substantially non-transmissive.
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公开(公告)号：US11498068B2
公开(公告)日：2022-11-15
申请号：US16632931
申请日：2019-01-02
发明人： Wenliang Yao , Haochen Cui , Peizhi Cai , Yuelei Xiao , Fengchun Pang , Yue Geng , Le Gu , Nan Zhao , Hui Liao , Yingying Zhao , Chuncheng Che
IPC分类号： B01L3/00
摘要： A microfluidic device, a microfluidic detection assembly and a detection method for the microfluidic device. The microfluidic device includes a first substrate and a second substrate; the first substrate and the second substrate are oppositely arranged to define a channel between the first substrate and the second substrate, the channel is configured for liquid to flow, the first substrate includes a base substrate and a plurality of control assemblies which are arranged on the base substrate along an extending direction of the channel, each of the plurality of control assemblies includes: a first electrode, a second electrode and a plurality of coils, and the first electrode is configured to input currents into the plurality of coils, and the plurality of coils are connected in parallel to the second electrode.
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公开(公告)号：US11103868B2
公开(公告)日：2021-08-31
申请号：US16338042
申请日：2018-10-11
发明人： Fengchun Pang , Peizhi Cai , Yue Geng , Le Gu , Yingying Zhao , Haochen Cui , Nan Zhao , Yuelei Xiao , Hui Liao , Chuncheng Che
IPC分类号： B01L3/00
摘要： The present disclosure provides a microfluidic chip, a biological detection device and a method. The microfluidic chip includes: a first substrate and a second substrate that are oppositely disposed; a first electrode and a second electrode that are oppositely disposed between the first substrate and the second substrate, the first electrode including a plurality of spaced first electrode units, and the second electrode including a plurality of spaced second electrode units, wherein the first electrode units are disposed oppositely to the second electrode units in one-to-one correspondence; a first dielectric layer and a second dielectric layer between the first electrode and the second electrode; a first hydrophobic layer and a second hydrophobic layer between the first dielectric layer and the second dielectric layer, wherein a gap is between the first hydrophobic layer and the second hydrophobic layer.
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公开(公告)号：US11383238B2
公开(公告)日：2022-07-12
申请号：US16626490
申请日：2019-07-26
发明人： Nan Zhao , Peizhi Cai , Haochen Cui , Yuelei Xiao , Fengchun Pang , Le Gu , Yingying Zhao , Hui Liao , Yue Geng , Wenliang Yao
摘要： A microfluidic apparatus is provided. The microfluidic apparatus includes an electrochromic layer including a plurality of individually independently addressable regions; a microfluidic layer defining a microfluidic channel for allowing a microfluid to pass therethrough; and a plurality of photodetectors configured to detect light transmit through the microfluid. The electrochromic layer is configured to be switched between a first state in which the plurality of individually independently addressable regions of the electrochromic layer are substantially transmissive, and a second state in which at least a first one of the plurality of individually independently addressable regions of the electrochromic layer in a region corresponding to a position of the microfluid is substantially transmissive, at least a second one of the plurality of individually independently addressable regions of the electrochromic layer outside the region corresponding to the position of the microfluid is substantially non-transmissive.
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公开(公告)号：US11344891B2
公开(公告)日：2022-05-31
申请号：US16768558
申请日：2019-11-13
发明人： Yingying Zhao , Peizhi Cai , Le Gu , Fengchun Pang , Yue Geng , Yuelei Xiao , Haochen Cui , Nan Zhao , Hui Liao , Wenliang Yao , Chuncheng Che
IPC分类号： B01L3/00
摘要： The present disclosure provides a microfluidic chip, including: first base substrate and a second base substrate opposite to each other; first electrode and second electrode between the first base substrate and the second base substrate and configured to control droplet to move between the first base substrate and the second base substrate according to voltages applied on the first electrode and the second electrode; light guide component configured to guide light propagating in the first base substrate to the droplet; shading component and detection component, shading component having light transmission regions spaced from each other, light transmission regions being configured to transmit light passing through the droplet to the detection component, wherein detection component is on second base substrate and is configured to obtain property of the droplet according to an intensity of the light passing through droplet and received from the light transmission regions.
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公开(公告)号：US11344889B2
公开(公告)日：2022-05-31
申请号：US16603648
申请日：2019-04-26
发明人： Haochen Cui , Peizhi Cai , Chuncheng Che , Fengchun Pang , Yingying Zhao , Yue Geng , Le Gu , Nan Zhao , Yuelei Xiao , Hui Liao
摘要： The embodiments of the present disclosure relate to a microfluidic chip. The microfluidic chip may include a substrate. The substrate may include an electrode layer on a base substrate, a dielectric layer on the electrode layer, and a lyophobic layer on the dielectric layer. The electrode layer may include a plurality of electrode units. Each of the plurality of electrode units may be configured to realize both droplet detection and droplet driving in response to a detection signal and a driving signal respectively.
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公开(公告)号：US20210322973A1
公开(公告)日：2021-10-21
申请号：US16603648
申请日：2019-04-26
发明人： Haochen Cui , Peizhi Cai , Chuncheng Che , Fengchun Pang , Yingying Zhao , Yue Geng , Le Gu , Nan Zhao , Yuelei Xiao , Hui Liao
摘要： The embodiments of the present disclosure relate to a microfluidic chip. The microfluidic chip may include a substrate. The substrate may include an electrode layer on a base substrate, a dielectric layer on the electrode layer, and a lyophobic layer on the dielectric layer. The electrode layer may include a plurality of electrode units. Each of the plurality of electrode units may be configured to realize both droplet detection and droplet driving in response to a detection signal and a driving signal respectively.
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9.发明申请公开(公告)号：US20200266393A1
公开(公告)日：2020-08-20
申请号：US16347707
申请日：2018-11-20
发明人： Guoqiang Tang , Yingsong Xu , Nan Zhao
IPC分类号： H01L51/52 , G09G3/3266 , G09G3/3291 , H01L27/28 , H01L51/56 , H01L27/32
摘要： The present disclosure relates to an organic luminescent substrate. The organic luminescent substrate may include a first organic luminescent field effect transistor and a second organic luminescent field effect transistor. The first organic luminescent field effect transistor may include a first gate electrode, a first electrode, a second electrode, and a first active luminescent layer. The second organic luminescent field effect transistor may include a second gate electrode, a third electrode, a fourth electrode, and a second active luminescent layer. One of the first organic luminescent field effect transistor and the second organic luminescent field effect transistor may be an N-type transistor and the other one may be a P-type transistor. The first gate electrode may be coupled to the second gate electrode.
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公开(公告)号：US11583855B2
公开(公告)日：2023-02-21
申请号：US17186186
申请日：2021-02-26
发明人： Hui Liao , Yingying Zhao , Bolin Fan , Wenliang Yao , Nan Zhao , Le Gu , Yongjia Gao
IPC分类号： B01L3/00 , G01N27/22 , G01N33/577
摘要： The present disclosure discloses a microfluidic structure, a microfluidic chip and a detection method. The microfluidic structure includes: a first base substrate and a second base substrate opposite to each other, an antibody area located between the first base substrate and the second base substrate and storing an enzyme-labeled first antibody, a cleaning area storing cleaning liquid, a signal substrate area storing a signal substrate solution and a detection area with a second antibody and an ion sensitive film fixed thereon, wherein all channel areas from the antibody area, the cleaning area and the signal substrate area to the detection area each have a driving electrode structure driving liquid drops to move; and the detection area has a thin film transistor connected with the ion sensitive film.
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