- 专利标题： Methods for in vitro memory B cell differentiation and transduction with VSV-G pseudotyped viral vectors
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申请号： US16267150申请日： 2019-02-04
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公开(公告)号： US11352603B2公开(公告)日： 2022-06-07
- 发明人: Mei Xu , Matthew Rein Scholz , Eric J. Herbig
- 申请人： IMMUSOFT CORPORATION
- 申请人地址： US WA Seattle
- 专利权人： IMMUSOFT CORPORATION
- 当前专利权人： IMMUSOFT CORPORATION
- 当前专利权人地址： US WA Seattle
- 代理机构： Cooley LLP
- 主分类号： C12N15/86
- IPC分类号： C12N15/86 ; C12N5/00 ; C12N5/0781 ; A61K48/00
摘要：
The present disclosure relates to the in vitro differentiation of memory B cells to plasmablasts or plasma cells and genetic modification of these cells to express a protein of interest, such as a specific antibody or other protein therapeutic.
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