Invention Grant
- Patent Title: BCL-2 inhibitors
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Application No.: US16795720Application Date: 2020-02-20
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Publication No.: US11365206B2Publication Date: 2022-06-21
- Inventor: Yi Chen , Yan Lou
- Applicant: Newave Pharmaceutical Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Newave Pharmaceutical Inc.
- Current Assignee: Newave Pharmaceutical Inc.
- Current Assignee Address: US CA Pleasanton
- Agency: McCarter & English, LLP
- Agent Yu Lu; Zhongyu “Alex” Wang
- Main IPC: A61P35/04
- IPC: A61P35/04 ; A61P35/00 ; A61P35/02 ; A61P37/00 ; C07D498/14 ; C07D513/14 ; A61K45/06 ; A61K31/542 ; A61K31/5383

Abstract:
The disclosure includes compounds of Formula (A): wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12, j, k, m, n, Y, W, W1, W2, W3, V, L, Z1, Q1, Q2, Q3, and Q4, are defined herein. Also disclosed is a method for treating a neoplastic disease, an autoimmune disease, or a neurodegenerative disease with these compounds.
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