- 专利标题: Risperidone-containing patch
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申请号: US16500446申请日: 2018-04-04
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公开(公告)号: US11382870B2公开(公告)日: 2022-07-12
- 发明人: Satoshi Kawakami , Manabu Sogabe , Taiki Shibata , Hiroaki Hasegawa
- 申请人: TEIKOKU SEIYAKU CO., LTD.
- 申请人地址: JP Kagawa
- 专利权人: TEIKOKU SEIYAKU CO., LTD.
- 当前专利权人: TEIKOKU SEIYAKU CO., LTD.
- 当前专利权人地址: JP Kagawa
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JPJP2017-075358 20170405,JPJP2017-253439 20171228
- 国际申请: PCT/JP2018/014412 WO 20180404
- 国际公布: WO2018/186441 WO 20181011
- 主分类号: A61K9/70
- IPC分类号: A61K9/70 ; A61K47/32 ; A61K47/12 ; A61P25/18 ; A61K47/14 ; A61K31/194 ; A61K31/20 ; A61K31/519
摘要:
The present invention provides a risperidone-containing patch having an excellent drug release property and patch physical properties. Specifically, the present invention provides a medical patch comprising an adhesive composition comprising risperidone or a pharmaceutically acceptable salt thereof; a carboxylic acid; a fatty acid ester; and an adhesive, characterized in that said adhesive is a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a sulfur residue of a mercapto group situated at the center, wherein the (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.99% by mass of the whole structural units in said star-shaped acrylic block polymer, and at least one of said chain polymer portions has a structural unit having a copolymer structure of polymerizable monomers comprising a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a polyfunctional monomer.
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