- 专利标题： Association of N-acetylcysteine and colistin for use in bacterial infections
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申请号： US16487227申请日： 2018-02-26
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公开(公告)号： US11382948B2公开(公告)日： 2022-07-12
- 发明人: Lucia Pallecchi , Francesco Sergio , Gian Maria Rossolini
- 申请人： Zambon S.P.A.
- 申请人地址： IT Bresso
- 专利权人： Zambon S.P.A.
- 当前专利权人： Zambon S.P.A.
- 当前专利权人地址： IT Bresso
- 代理机构： Silvia Salvadori, P.C.
- 代理商 Silvia Salvadori
- 优先权： EP17158241 20170227
- 国际申请： PCT/EP2018/054611 WO 20180226
- 国际公布： WO2018/154091 WO 20180830
- 主分类号： A61K38/12
- IPC分类号： A61K38/12 ; A61K31/198 ; A61K31/164 ; A61P31/04
摘要：
A synergistic pharmacological association of N-acetylcysteine (NAC) and colistin for use in the treatment of a bacterial infection caused by one or more pathogens selected from S. maltophilia and A. baumannii strains, in particular a bacterial infection associated with a respiratory tract disease, such as a chronic respiratory tract disease comprising cystic fibrosis (CF), bronchiectasis non CF and chronic obstructive pulmonary disease (COPD) is described.
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