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公开(公告)号：US20220370549A1
公开(公告)日：2022-11-24
申请号：US17664232
申请日：2022-05-20
申请人： Zambon S.P.A.
IPC分类号： A61K38/12 , A61P31/04 , A61K31/198
摘要： A synergistic pharmacological association of N-acetylcysteine (NAC) and colistin for use in the treatment of a bacterial infection caused by one or more pathogens selected from S. maltophilia and A. baumannii strains, in particular a bacterial infection associated with a respiratory tract disease, such as a chronic respiratory tract disease comprising cystic fibrosis (CF), bronchiectasis non CF and chronic obstructive pulmonary disease COPD is described.
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公开(公告)号：US11382948B2
公开(公告)日：2022-07-12
申请号：US16487227
申请日：2018-02-26
申请人： Zambon S.P.A.
IPC分类号： A61K38/12 , A61K31/198 , A61K31/164 , A61P31/04
摘要： A synergistic pharmacological association of N-acetylcysteine (NAC) and colistin for use in the treatment of a bacterial infection caused by one or more pathogens selected from S. maltophilia and A. baumannii strains, in particular a bacterial infection associated with a respiratory tract disease, such as a chronic respiratory tract disease comprising cystic fibrosis (CF), bronchiectasis non CF and chronic obstructive pulmonary disease (COPD) is described.
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公开(公告)号：US20200093774A1
公开(公告)日：2020-03-26
申请号：US16468716
申请日：2017-12-13
申请人： Zambon S.P.A.
IPC分类号： A61K31/197 , A61P31/04
摘要： The present invention relates to N-acetylcysteine for the use in the treatment of bacterial infections caused by a pathogen selected from Burkholderia cepacia complex (BCC) and Stenotrophomonas maltophilia (S. maltophilia) strains.
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公开(公告)号：US12102660B2
公开(公告)日：2024-10-01
申请号：US17664232
申请日：2022-05-20
申请人： Zambon S.P.A.
IPC分类号： A61K38/12 , A61K31/164 , A61K31/198 , A61P31/04
CPC分类号： A61K38/12 , A61K31/198 , A61P31/04
摘要： A synergistic pharmacological association of N-acetylcysteine (NAC) and colistin for use in the treatment of a bacterial infection caused by one or more pathogens selected from S. maltophilia and A. baumannii strains, in particular a bacterial infection associated with a respiratory tract disease, such as a chronic respiratory tract disease comprising cystic fibrosis (CF), bronchiectasis non CF and chronic obstructive pulmonary disease COPD is described.
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公开(公告)号：US11918552B2
公开(公告)日：2024-03-05
申请号：US17134719
申请日：2020-12-28
申请人： Zambon S.P.A.
IPC分类号： A61K31/197 , A61P31/04
CPC分类号： A61K31/197 , A61P31/04
摘要： The present invention relates to N-acetylcysteine for the use in the treatment of bacterial infections caused by a pathogen selected from Burkholderia cepacia complex (BCC) and Stenotrophomonas maltophilia (S. maltophilia) strains.
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公开(公告)号：US20210128678A1
公开(公告)日：2021-05-06
申请号：US16487227
申请日：2018-02-26
申请人： Zambon S.P.A.
IPC分类号： A61K38/12 , A61K31/198 , A61P31/04
摘要： The present invention relates to a synergistic pharmacological association of NAC and colistin for use in the treatment of a bacterial infection caused by one or more pathogens selected from S. maltophilia and A. baumannii strains, in particular a bacterial infection associated with a respiratory tract disease, such as a chronic respiratory tract disease comprising CF, bronchiectasis non CF and COPD.
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公开(公告)号：US20210113508A1
公开(公告)日：2021-04-22
申请号：US17134719
申请日：2020-12-28
申请人： Zambon S.P.A.
IPC分类号： A61K31/197 , A61P31/04
摘要： The present invention relates to N-acetylcysteine for the use in the treatment of bacterial infections caused by a pathogen selected from Burkholderia cepacia complex (BCC) and Stenotrophomonas maltophilia (S. maltophilia) strains.
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