Invention Grant
- Patent Title: Biarylmethyl heterocycles
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Application No.: US16311835Application Date: 2017-06-28
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Publication No.: US11407733B2Publication Date: 2022-08-09
- Inventor: Eldon Scott Priestley , Samuel Kaye Reznik , Edward H. Ruediger , James R. Gillard , Oz Scott Halpern , Wen Jiang , Jeremy Richter , Rejean Ruel , Sasmita Tripathy , Wu Yang , Xiaojun Zhang
- Applicant: Universite de Montreal , Bristol-Myers Squibb Company
- Applicant Address: CA Montreal; US NJ Princeton
- Assignee: Universite de Montreal,Bristol-Myers Squibb Company
- Current Assignee: Universite de Montreal,Bristol-Myers Squibb Company
- Current Assignee Address: CA Montreal; US NJ Princeton
- Agency: Hoffmann & Baron, LLP
- International Application: PCT/US2017/039646 WO 20170628
- International Announcement: WO2018/005591 WO 20180104
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D403/10 ; C07D403/12 ; C07D403/14 ; C07D409/14 ; C07D417/14 ; C07D491/107 ; C07D401/10 ; C07D235/26 ; C07D413/10 ; C07D471/04 ; C07D257/04 ; C07D405/14 ; C07D233/90 ; C07D498/10 ; C07D413/14 ; A61P9/04 ; A61K31/41 ; A61K31/4245 ; A61K31/427 ; A61K31/437 ; A61K31/4439 ; A61K31/4709 ; A61K31/497 ; A61K31/501 ; C07D239/20 ; C07D271/07
Abstract:
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are biased agonists, or β-Arrestin agonists of the angiotensin II receptor, which may be used as medicaments.
Public/Granted literature
- US20190202808A1 BIARYLMETHYL HETEROCYCLES Public/Granted day:2019-07-04
Information query
