- 专利标题: Compounds and methods for treating, detecting, and identifying compounds to treat apicomplexan parasitic diseases
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申请号: US16063877申请日: 2016-12-20
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公开(公告)号: US11414385B2公开(公告)日: 2022-08-16
- 发明人: Rima McLeod , Martin McPhillie , Colin W. G. Fishwick , Hernan Alejandro Lorenzi , Kai Wang , Taek-Kyun Kim , Yong Zhou , Leroy E. Hood , Ying Zhou , Kamal El Bissati , Mark Hickman , QiGui Li , Craig Roberts
- 申请人: The University of Chicago , University of Leeds , The J. Craig Venter Institute , Institute For Systems Biology , U.S. Government, as represented by The Secretary of The Army Medical Command (MEDCOM) , The University of Strathclyde
- 申请人地址: US IL Chicago; GB Leeds; US MD Rockville; US WA Seattle; US MD Fort Detrick; GB Glasgow
- 专利权人: The University of Chicago,University of Leeds,The J. Craig Venter Institute,Institute For Systems Biology,U.S. Government, as represented by The Secretary of The Army Medical Command (MEDCOM),The University of Strathclyde
- 当前专利权人: The University of Chicago,University of Leeds,The J. Craig Venter Institute,Institute For Systems Biology,U.S. Government, as represented by The Secretary of The Army Medical Command (MEDCOM),The University of Strathclyde
- 当前专利权人地址: US IL Chicago; GB Leeds; US MD Rockville; US WA Seattle; US MD Fort Detrick; GB Glasgow
- 代理机构: McDonnell Boehnen Hulbert & Berghoff LLP
- 国际申请: PCT/US2016/067795 WO 20161220
- 国际公布: WO2017/112678 WO 20170629
- 主分类号: C07D215/233
- IPC分类号: C07D215/233 ; A61P33/06 ; C07D401/12 ; C07D405/12 ; C07D471/04 ; C07D487/04
摘要:
Disclosed herein; are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.
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