Invention Grant
- Patent Title: Core-shell microneedle platform for transdermal and pulsatile drug/vaccine delivery and method of manufacturing the same
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Application No.: US16293588Application Date: 2019-03-05
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Publication No.: US11426570B2Publication Date: 2022-08-30
- Inventor: Thanh D. Nguyen , Khanh Tran
- Applicant: University of Connecticut
- Applicant Address: US CT Farmington
- Assignee: University of Connecticut
- Current Assignee: University of Connecticut
- Current Assignee Address: US CT Farmington
- Agency: Michael Best & Friedrich LLP
- Main IPC: A61M37/00
- IPC: A61M37/00 ; A61B17/20 ; B29C41/00 ; B29C43/00 ; B29C65/02 ; B29C43/32 ; B29C43/02 ; B29C39/00 ; B29C39/02
Abstract:
A core-shell microneedle system and a method of manufacturing the microneedle system provides a pulsatile drug delivery system which is programmed to release drugs/vaccines at predictable times using biodegradable polymers and with controllable dosages. This microneedle system can be fully embedded into the skin and then release drugs/vaccines as sharp bursts in a timely manner, similar to multiple bolus injections.
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