- 专利标题： Antitumor compound for activating JWA gene and degrading HER2, preparation method thereof, and application thereof
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申请号： US16992089申请日： 2020-08-12
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公开(公告)号： US11427575B2公开(公告)日： 2022-08-30
- 发明人: Jianwei Zhou , Yanlin Ren , Dongyin Chen , Yefei Huang , Aiping Li
- 申请人： Jianwei Zhou
- 申请人地址： CN Nanjing
- 专利权人： Jianwei Zhou
- 当前专利权人： Jianwei Zhou
- 当前专利权人地址： CN Nanjing
- 代理机构： Matthias Scholl P.C.
- 代理商 Matthias Scholl
- 优先权： CN201910739357.4 20190812
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; A61P35/00
摘要：
A compound as shown in formula I. R1 is selected from the group consisting of —OH, —CH3, —CH2CH3, —OCH3, —OCH2CH3; R2 is selected from the group consisting of —H, —OH, —CH3, —CH2CH3, —CH2CH2CH3, —OCH3, —OCH2CH2CH3; R3 is selected from the group consisting of —F, —Cl, —Br, —I, —CF3; R4 is selected from the group consisting of —H, —F, —Cl, —Br, —I, —CF3; and R5 is selected from the group consisting of —H, —CH3, —CH2CH3.
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