- 专利标题： Bromodomain inhibitor compound and use thereof
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申请号： US16962347申请日： 2019-01-11
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公开(公告)号： US11427593B2公开(公告)日： 2022-08-30
- 发明人: Bing Zhou , Cheng Luo , Zizhou Li , Yaxi Yang , Shijie Chen , Hong Ding , Hualiang Jiang , Gang Qiao , Xinjun Wang , Senhao Xiao
- 申请人： SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES , SUZHOU SUPLEAD LIFE SCIENCES CO., LTD.
- 申请人地址： CN Shanghai; CN Jiangsu
- 专利权人： SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES,SUZHOU SUPLEAD LIFE SCIENCES CO., LTD.
- 当前专利权人： SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES,SUZHOU SUPLEAD LIFE SCIENCES CO., LTD.
- 当前专利权人地址： CN Shanghai; CN Jiangsu
- 代理机构： Rimon Law
- 代理商 Ping Wang
- 优先权： CN201810040756.7 20180116,CN201811081153.8 20180917
- 国际申请： PCT/CN2019/071258 WO 20190111
- 国际公布： WO2019/141131 WO 20190725
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61P35/00 ; A61P35/02
摘要：
The present invention relates to a bromodomain inhibitor. Provided are a compound represented by general formula I or a pharmaceutically acceptable salt, enantiomer, diastereomer, atropisomer, racemate, polymorph, solvate, or isotopically labeled compound (including deuterium substitution) thereof, a preparation method of the same, a pharmaceutical composition comprising the same, and a pharmaceutical use thereof.
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