专利检索 ap:("SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES" OR "SUZHOU SUPLEAD LIFE SCIENCES CO., LTD.") AND inv:"Zizhou Li" 第 1 页

1.

发明授权
Bromodomain inhibitor compound and use thereof 有权

公开(公告)号：US11427593B2

公开(公告)日：2022-08-30

申请号：US16962347

申请日：2019-01-11

申请人： SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES , SUZHOU SUPLEAD LIFE SCIENCES CO., LTD.

发明人： Bing Zhou , Cheng Luo , Zizhou Li , Yaxi Yang , Shijie Chen , Hong Ding , Hualiang Jiang , Gang Qiao , Xinjun Wang , Senhao Xiao

IPC分类号： C07D487/04 , A61P35/00 , A61P35/02

摘要： The present invention relates to a bromodomain inhibitor. Provided are a compound represented by general formula I or a pharmaceutically acceptable salt, enantiomer, diastereomer, atropisomer, racemate, polymorph, solvate, or isotopically labeled compound (including deuterium substitution) thereof, a preparation method of the same, a pharmaceutical composition comprising the same, and a pharmaceutical use thereof.