• Patent Title: Modified filamentous fungal host cell for encoding a secreted polypetide of interest
  • Application No.: US17284163
    Application Date: 2019-10-08
  • Publication No.: US11434475B2
    Publication Date: 2022-09-06
  • Inventor: Hiroaki Udagawa
  • Applicant: Novozymes A/S
  • Applicant Address: DK Bagsvaerd
  • Assignee: Novozymes A/S
  • Current Assignee: Novozymes A/S
  • Current Assignee Address: DK Bagsvaerd
  • Agent Eric Fechter
  • Priority: EP18199385 20181009
  • International Application: PCT/EP2019/077205 WO 20191008
  • International Announcement: WO2020/074502 WO 20200416
  • Main IPC: C12N9/20
  • IPC: C12N9/20 C12N1/14 C07K14/38 C12N9/34
Modified filamentous fungal host cell for encoding a secreted polypetide of interest
Abstract:
The present invention relates to filamentous fungal cells secreting a polypeptide of interest, wherein the expression of a citT gene is altered, reduced or eliminated compared to a non-mutated otherwise isogenic or parent cell, and methods of producing a secreted polypeptide of interest in said cells as well as methods of producing said cells.
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