- 专利标题: Biomimetic vesicles and uses thereof
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申请号: US17057415申请日: 2019-05-23
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公开(公告)号: US11446392B2公开(公告)日: 2022-09-20
- 发明人: K. Craig Kent , Shaoqin Gong , Lianwang Guo , Bowen Wang , Guojun Chen , Go Urabe
- 申请人: Ohio State Innovation Foundation , Wisconsin Alumni Research Foundation
- 申请人地址: US OH Columbus; US WI Madison
- 专利权人: Ohio State Innovation Foundation,Wisconsin Alumni Research Foundation
- 当前专利权人: Ohio State Innovation Foundation,Wisconsin Alumni Research Foundation
- 当前专利权人地址: US OH Columbus; US WI Madison
- 代理机构: Thomas | Horstemeyer, LLP
- 国际申请: PCT/US2019/033861 WO 20190523
- 国际公布: WO2019/226963 WO 20191128
- 主分类号: A61K47/69
- IPC分类号: A61K47/69 ; A61K9/51 ; A61K45/06 ; B82Y5/00
摘要:
The present disclosure relates to unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. The disclosed compositions are useful for treating a subject with a disease or condition, such as a cardiovascular disease. In a further aspect, the cardiovascular disease can be a vascular stenosis or restenosis. Also described herein are methods of making and using the unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
公开/授权文献
- US20210205473A1 BIOMIMETIC VESICLES AND USES THEREOF 公开/授权日:2021-07-08