Invention Grant
- Patent Title: Treatment of disorders associated with inflammation
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Application No.: US16955393Application Date: 2018-12-20
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Publication No.: US11446496B2Publication Date: 2022-09-20
- Inventor: Margarita J. Vervoordeldonk , Eric Irwin , Daniel John Chew , Matteo Donega , Cindy Cleypool , Isha Gupta
- Applicant: Galvani Bioelectronics Limited
- Applicant Address: GB Middlesex
- Assignee: Galvani Bioelectronics Limited
- Current Assignee: Galvani Bioelectronics Limited
- Current Assignee Address: GB Middlesex
- Agency: Banner & Witcoff, Ltd.
- International Application: PCT/GB2018/053731 WO 20181220
- International Announcement: WO2019/122908 WO 20190627
- Main IPC: A61N1/00
- IPC: A61N1/00 ; A61N1/36 ; A61N1/05 ; A61N1/08

Abstract:
Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.
Public/Granted literature
- US20210093862A1 TREATMENT OF DISORDERS ASSOCIATED WITH INFLAMMATION Public/Granted day:2021-04-01
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